I've tried various Sierra games that work nicely: SQ4, KQ5, KQ1Remake, and KQ2. Wolfenstein 3D works nicely, though. I plan to try a few more later on (didn't have much time today to do it). I already tried running Windows 3.11 on it and sadly it does not work
I'm very excited about this, though. With the addition of DOSBox to the Wii's ever-growing supported Homebrew application list the Wii has become my number one gaming system of all time with the support of emulators, ScummVM, DOSBox, and of course Gamecube and Wii games themselves. DOSBox and ScummVM themselves cover a LOT of games, but that along with all the emulators available (NES, GBA, SNES, GEN, SMS, GG, PSX, Saturn, Atari, Amiga, AppleIIe, and the list goes on and on), the possibilities are near endless.